Isoflavones to Control Hypercholesterolemia
Hypercholesterolemia is a serious risk factor for cardiovascular disease.
I've heard that isoflavones may be effective in improving hypercholesterolemia.
Here is a study that investigated how much they changed in terms of numbers.
The study is as follows
There were 208 participants from five randomized trials, 104 in the intervention group and 104 in the control group.The intervention period ranged from 3 to 6 months.Four trials reported results from non-Asian populations that were published in English.One trial reported results from a Chinese population published in Chinese.
Overall, the risk of bias in the selected trials was high or unknown. There were no outcome data on death from any cause, morbidity, complications, health-related quality of life, or costs.
Two trials reported adverse effects such as gastrointestinal discomfort (bloating and constipation) and an increased number of hot flashes.
No serious adverse events were found in any of the studies.
When compared to placebo, isoflavones had a marginally significant effect on triglycerides.(Mean difference (MD) -0.46 mmol/L (95% confidence interval (CI) -0.84 to -0.09. P = .02. 52 participants. 2 trials)
No statistically significant effects on total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol in favor of isoflavones were demonstrated.
Qin Y, Niu K, Zeng Y, Liu P, Yi L, Zhang T, Zhang QY, Zhu JD, Mi MT. isoflavones for hypercholesterolemia in adults Cochrane Database of Systematic Reviews 2013, No. 6. Number: CD009518. doi: 10.1002 / 14651858.CD009518.pub2.
Results.
We could not conclude that hypercholesterolemia can be changed.
Actually, soy is good for cholesterol! has been around since before 2009. In fact, it seems that soy has been said to be good for cholesterol since before 2009, and there are still professional organizations that say it is good despite the results.
There have been a few cases of adverse events reported due to excessive intake, but these have not been confirmed in this paper.
The conclusion is that we cannot expect too much from isoflavone. The last thing I can say is, don't eat too much! The last thing to do is to eat too much!
