KeiS a medical professional

This is a blog about the scientific basis of medicine. A judo therapist reads research papers for study and writes about them.

sponsorlink

Evidence for 4 ways to control blood sugar levels

Thursday, June 3, 2021

Blood sugar levels

Interventions to control blood sugar levels

Sweet potatoes

The sweet potato (Ipomoea batatas) is a plant found in tropical and subtropical zones. It is one of the most nutritious tropical and subtropical vegetables.

Sweet potatoes are not only cooked in countries in the Asia-Pacific region, Africa and North America, but are also used in traditional medicine for the treatment of diabetes.Can sweet potatoes work as a cure for diabetes? We decided to investigate whether there is enough evidence from medical trials to show that sweet potatoes

The trials

The randomized controlled trial included a total of 140 participants from three studies that evaluated the effects of sweet potatoes on type 2 diabetes compared to a sham (placebo).

All of these studies are of very low quality.

Two studies with 122 participants showed improved long-term metabolic control of blood glucose levels as measured by glycosylated hemoglobin A1c (HbA1c). The duration of treatment ranged from 6 weeks to 5 months. No studies have examined diabetic complications, death from any cause, health-related quality of life, well-being, functional outcomes, or costs.

Side effects are mostly mild, with abdominal distention and pain reported.

Oi CP, Loke SC Sweet Potatoes for Type 2 Diabetes Systematic Review of the Cochrane Database 2013, No. 9. Number: CD009128. doi: 10.1002 / 14651858.CD009128.pub3.

In our experiment, we continued to consume foods that contained 4 grams of sweet potato components per day.It seems that HbA1c levels were managed in the long term.

Cinnamon

The paper presented here evaluates the effects of cinnamon in diabetics.

The study is as follows

Type 1 and type 2 diabetics were included.

Randomized controlled trials were identified from 10 studies with a total of 577 participants.All but two trials had a high or unknown risk of bias, and they were assessed as having a moderate risk of bias.

Oral single-agent cinnamon (mainly Cinnamomum cassia) was administered at an average dose of 2 g daily for a period ranging from 4 to 16 weeks.

The effect of cinnamon on fasting blood glucose levels was inconclusive.

There were no statistically significant differences in glycosylated hemoglobin A1c (HbA1c), serum insulin, or postprandial glucose between the cinnamon group and the control group.There were insufficient data to pool the results for insulin sensitivity.

No studies reported health-related quality of life, morbidity, mortality, or costs. Adverse reactions to oral cinnamon were rare and generally mild.

MJ, Kumar S. Leach Cinnamon for Diabetes Mellitus. Cochrane Database of Systematic Reviews 2012, No. 9. Number: CD007170. DOI: 10.1002 / 14651858.CD007170.pub2.

The conclusion is that cinnamon, which some have expected to be effective, did not significantly control blood sugar levels.

Ayurveda

The study included.

354 participants (172 treated, 158 control, 24 unknown) from 6 trials.

Duration of treatment ranged from 3 to 6 months.

All studies were conducted in adults with type 2 diabetes.

Significant reductions in glycosylated hemoglobin A1c (HbA1c), fasting blood sugar (FBS), or both were observed compared to placebo or without additional treatment.

Pancreatic tonic and Hyponidd treatment. Data on HbA1c and FBS levels were not available in these studies. One study of treatment with a pancreatic tonic did not detect any significant changes in health-related quality of life. The main adverse effect reported is drug hypersensitivity. The main adverse effect reported was drug hypersensitivity (one study, one patient in the treatment group).

Postprandial blood glucose levels (PPBS) were lower among participants treated with Diabecon, unchanged with Hyponidd, and lower among participants treated with Cialis. unchanged in Hyponidd and higher in patients treated with Cogent DB.

Treatment with Pancreas tonic and Hyponidd did not significantly affect the lipid profile, but patients treated with Inolter had significantly higher HDL cholesterol and lower LDL cholesterol, as well as lower triglycerides.

Participants treated with Cogent DB also had lower total cholesterol and triglycerides.Studies of treatment with Diabecon have reported elevated fasting insulin levels. One study of Diabecon treatment reported higher stimulated insulin levels and fasting C-peptide levels in the treatment group.

There was no significant difference in fasting and stimulated C-peptide and insulin levels with Hyponidd, Cogent DB, and pancreatic tonic treatments. Inolter's study did not evaluate these results.

Studies examining diabetic complications, death from any cause, and economic data were not reported or designed to be examined.

Sridharan K, Mohan R, Ramaratnam S, Panneerselvam D. Ayurvedic treatment for diabetes mellitus. Cochrane Database of Systematic Reviews 2011, No. 12. Number: CD008288. doi: 10.1002 / 14651858.CD008288.pub2.

Low GI diet

Studies include.

A total of 402 participants from 11 randomized controlled trials were included in the study.

There was a significant reduction in glycated hemoglobin A1c (HbA1c) in the parallel group trials, with a weighted mean difference (WMD) of -0.5% and a 95% confidence interval (CI) of -0.9 to -0.1, P = .02.

In the crossover study, the WMD was -0.5%, with a 95% CI of -1.0 to -0.1, P = 0.03.

In other studies, diets were compared with a measured carbohydrate replacement diet. (35% vs. 66%, P = .006)

No mortality, morbidity, or costs reported.

Thomas D, Elliott EJ. Hypoglycemic index, or low glycemic load, and diet for diabetes mellitus. Cochrane Database of Systematic Reviews 2009, Issue 1. Number: CD006296. doi: 10.1002 / 14651858.CD006296.pub2.

Summary.

A study was conducted that lasted from 1 to 12 months.

The results measured by HbA1c showed a decrease of 0.5% in some cases.

As a criterion for diabetes, a fasting blood glucose level of 110 mg/dL or higher is high (100-109 is normal high). If the HbA1c (normal value 4.6-6.2%) is measured in the combined health checkup, then Diabetes can also be diagnosed.

This result of a 0.5% decrease is considered statistically and clinically important.

QooQ