The largest CDCCOVID-19 vaccine efficacy study in health care workers shows that the mRNA vaccine is 94% effective.
The new CDC study adds to a growing body of real-world evidence (outside of the clinical trial setting) showing that COVID-19 mRNA vaccines approved by the Food and Drug Administration (FDA) protect health care providers (HCPs) from COVID-19. The mRNA vaccines (Pfizer-BioNTech and Moderna) reduced the risk of COVID-19 infection in fully vaccinated HCP by 94%. This evaluation, conducted in a separate research network with a larger sample size over a larger geographic area than the clinical trial, independently confirms the findings of the U.S. vaccine effectiveness study among health care providers first reported on March 29.
Adapted from the U.S. Department of Health and Human Services website.
Commentary
A case-control comparison of vaccination status among SARS-CoV-2 positive/negative participants found that of 1,843 participants, 623 were positive and 1,220 were negative. Vaccine efficacy estimates were calculated by comparing the odds of vaccination, with narrower confidence intervals and more accurate estimates of vaccine efficacy than previous CDC findings, according to the study.
In the current report, fully vaccinated health care workers reported a 94% reduction. Complete vaccination is defined as "at least 7 days after the second dose of vaccine", while a single dose of vaccine has been reported to reduce the number of cases by 82%. These findings resulted in support of the CDC's recommendation that everyone should be vaccinated with both doses of mRNACOVID-19 vaccine.
I am writing this in English, but it is something I would like Japanese people to see.