Functional signature of the entire characteristic anger connectome

https://doi.org/10.1177/21677026211030240

Explanation

Past research on anger and brain correlates has a history of focusing on small sample sizes and relatively small regions of interest, and has been limited by the unreliability of testing and retesting functional brain measures.

This study was investigating against these limitations by conducting a data-driven analysis of variability in functional connectivity across the connectome in a sample of 1,048 young adult volunteers.

Multidimensional matrix regression analysis showed that self-reported trait anger mapped to variability in whole-brain functional connectivity patterns in three brain regions that serve behavior-related functions.

Next, we also showed that trait anger undergoes somatic motor, emotional, self-referential, and visual informational processes.

These findings provide new neuroimaging evidence for interpreting trait anger as a larger tendency toward elicited behavior.