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This is a blog about the scientific basis of medicine. A judo therapist reads research papers for study and writes about them.

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The Scientific Basis for Cellulite Removal Treatments

Monday, May 3, 2021

treatment

This time, we're going to talk about cellulite removal.

Are you concerned about cellulite on your body?

I think there are people of both sexes who are concerned about cellulite from an aesthetic standpoint, but when it comes to cellulite removal, some people tend to think of women.Nowadays, men are also becoming more interested in beauty, and many of them are interested in cellulite removal procedures.

The question is, can cellulite be completely removed? The answer is "no," according to current research.

The answer is "no," according to current research.

Contents of the study

Evidence for topical treatments

Topical medications combined with aggressive massage is what is employed in the earliest attempts to treat cellulite.These topical agents have several peer-reviewed publications with promising data, but studies are small and long-term follow-up is not available.

All that can be said is that certain formulations can improve collagen production and reduce skin laxity, but they are not effective against cellulite, which requires extensive fat, collagen, and connective tissue remodeling.

Therefore, it may be impossible to try to remove cellulite with XX that is applied.

Evidence of Radio Frequency Therapy

RF devices deliver thermal energy to the dermis/subcutaneous plane via electrodes.

They are used for cellulite removal because increasing the tissue temperature in the target area stimulates collagen degeneration, remodeling and neoplasia, but also triggers lipolysis.These latest generation RF devices have been studied and shown to be effective in clinical trials to reduce the appearance of cellulite.

(Luebberding et al, 2015, Romero et al, 2008, Sadick, 2009, Sadick and Magro, 2007, Sadick and Mulholland, 2004, Wanitphakdeedecha et al, 2017)

In a study by Sadick and Magro (2007) in which 16 subjects with cellulite were treated with the VelaSmooth system twice a week for 6 weeks, over 50% of the subjects had a 71.87% reduction in thigh circumference and a 25% improvement in cellulite.

In another study, in which 35 female subjects with cellulite received 8-16 treatments twice a week using the VelaSmooth device, 70% of the patients showed a reduction in thigh circumference after 4 weeks of treatment, and 100% of the patients showed some improvement.

Although this is a good result, we cannot say that it removes cellulite, as the quality of evidence for this result is considered low due to the small sample size.

Evidence for laser therapy

In a multicenter clinical trial in which 57 patients underwent three-stage cellulite treatment using a 1440 nm Nd:YAG laser with a lateral irradiation fiber and temperature-sensing cannula, the mean improvement scores were 1.7 for dimpling and 1.1 for contour irregularity.

 At 6 months follow-up, the mean satisfaction score on a 6-point scale was 5.6 for physicians and 5.3 for patients.The outcomes were reported to be acceptable to the patients, but removal? It is considered difficult to say in terms of

Evidence for ultrasound therapy

The efficacy of ESWT in 15 individuals was assessed, and eight sessions were conducted over a four-week period.They concluded that ESWT was effective in improving body contour (i.e., reduction in circumference and fat layer) as well as the appearance of cellulite after 3 months of treatment.

They also evaluated the effectiveness of ESWT in treating cellulite in 30 women who underwent 12 sessions over 6 weeks.

The treatment reduced the severity of cellulite from baseline and the mean thickness of subcutaneous adipose tissue until 12 weeks after the last treatment session (subjects with severe cellulite: 60%-38%).

(28.3±6.5 mm to 26.7±6.1 mm; 2. p<.001)

This treatment also improved patients' quality of life, and no serious adverse events were reported!

Evidence from subdivision

Manual subcisions for the treatment of cellulite have also been evaluated.

During this procedure, a local anesthetic (a vasoconstrictor containing lidocaine) is used to numb the area, a needle (18 G) is inserted under the skin, and a fanning technique is used to release the fiber strings of cellulite.

Although effective, the main drawback of this treatment is the side effects, which include edema, discomfort, pain, and bruising. (Hexcel and Mazzuco, 2000)

Recently, a novel tissue stabilization-guided supplemental (TS - GS) system (Cellfina System; Merz North America, Inc., Raleigh, NC) has been developed and approved by the FDA for the improvement of cellulite in the buttocks and thighs of adult women. The Cellfina System has been developed by Merz North America, Inc.

Cellfina's advantages over traditional manual incisions with needles include precise control of treatment depth and tissue area (fibrous septum), and a unique vacuum-assisted design.Cellfina has been shown to improve cellulite in multicenter clinical trials, with results lasting beyond three years. (Kaminer et al., 2017)

In the most recent clinical trial, 45 subjects were followed for up to three years after a single treatment with the TS-GS system.

The results of this trial show a long-term reduction in the appearance of cellulite following TS-GS.

Conclusion.

Despite multiple treatment approaches attempting to treat cellulite, there are no successful long-term proven procedures.

Topical agents, injection therapy, and energy-based devices can improve the appearance of cellulite, sometimes to a satisfactory degree, but they will never eradicate cellulite because this involves extensive tissue remodeling.

In the author's opinion, the best clinical results are from a combination approach, where internal and external approaches are used in a strategic and stepwise manner to produce synergistic results.For example, injections of CaHa, followed by five weekly treatments with an RF device, may improve severe cellulite about three months after the last treatment.

Another example of a combination strategy could be six sessions of weekly sound wave therapy, followed by unilateral firing of a 1440nm laser.

Larger studies need to be conducted to evaluate the long-term outcomes of cellulite treatment in terms of safety, efficacy, and patient satisfaction, especially with regard to combination therapy.

Sadiq N. Treatment for cellulite. Int J Womens Dermatol. 2018; 5(1): 68-72. Published October 22, 2018. doi: 10.1016 / j.jwd.2018.09.002

Conclusion 

Although some people may believe that cellulite can be "completely" eliminated by taking the word "cellulite removal" at face value, the results show that there are currently no interventions that can completely eliminate cellulite.

However, since this kind of treatment is often expensive, and it may be difficult to keep doing it, many people may not know whether it will actually reduce the amount of cellulite.Since cellulite is caused by obesity, people who are concerned about becoming obese can take measures now, but there are no suggestions for preventive measures or beneficial treatments for people who are actually suffering from cellulite.

In a way, people who remove cellulite completely are considered "perfectionists," and for them, even if they are able to remove cellulite, they may still have problems finding the next problem.

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