It's not even flu season at all.
If you're wondering about the issue of vaccines, here's some good news.
How much of a difference does it make? Here is a paper that investigates this question.First, the impact of the flu in adults is that they miss work.And vaccination of pregnant women is recommended internationally.
The paper presented aimed to evaluate the effectiveness (efficacy, effectiveness, and harm) of the vaccine against influenza in healthy adults, including pregnant women.
What were the studies?
More than 80,000 people from 52 clinical trials were included.
The study included more than 80,000 people from 52 clinical trials that administered an inactivated parenteral flu vaccine.Results from 25 studies comparing inactivated parenteral influenza vaccine with placebo or no control group are also included.
The studies were conducted between 1969 and 2009.The studies were conducted over a single flu season in North America, South America, and Europe between 1969 and 2009.The studies were conducted over a single flu season in North America, South America and Europe between 1969 and 2009.The studies were conducted over a single influenza season in North America, South America, and Europe between 1969 and 2009. Excluding hospitalizations, we did not consider studies at high risk of bias to influence outcome results.
The inactivated influenza vaccine probably reduces influenza in healthy adults from 2.3% without vaccination to 0.9%.(Risk ratio (RR) 0.41, 95% confidence interval (CI) 0.36-0.47, 71,221 participants, moderate evidence of certainty)
Immunization may slightly reduce the risk of hospitalization in healthy adults from 14.7% to 14.1%.However, the CI is wide and does not rule out a large benefit.(RR 0.96, 95% CI 0.85-1.08, 11,924 participants, low certainty evidence)
Vaccination may result in little or no small reduction in days away from work. (-0.04 days, 95% CI -0.14 to 0.06 days; low-certainty evidence)And the inactivated vaccine causes an increase in fever from 1.5% to 2.3%.
We identified one RCT and one controlled clinical trial evaluating the effect of vaccination in pregnant women.The efficacy of inactivated vaccines containing pH1N1 against influenza was found to be 50% in mothers and 49% in infants up to 24 weeks.There were no data on the efficacy of seasonal influenza during pregnancy.Evidence from observational studies shows that the efficacy of influenza vaccine against ILI in pregnant women is 24% (95% CI 11% to 36%, NNV 94), and the efficacy against influenza in newborns of vaccinated women is 41% (95% CI 6%).
The live aerosol vaccine has an overall efficacy equivalent to 46 NNV.One or two doses of all virion 1968-1969 pandemic vaccines.performance was higher against ILI and influenza.The impact on hospitalization during the 1968-1969 pandemic was limited.
Administration of both seasonal and 2009 pandemic vaccines during pregnancy had no significant effect on abortion or neonatal deaths, but this was based on an observational data set.Pandemic refers to a widespread epidemic disease.
Demicheli V, Jefferson T, Ferroni E, Rivetti A, Di Pietrantonj C. Vaccines for influenza prevention in healthy adults. Cochrane Database of Systematic Reviews 2018, No. 2. Number: CD001269. doi: 10.1002 / 14651858.CD001269.pub6.
So, how did it go?
The results showed that in healthy adults, when given a live parenteral vaccine.
may reduce influenza from 2.3 to 1% based on 59% vaccine effectiveness.
The results depend on the type of vaccine, but it is up to you, the reader, to decide what you think of these numbers.First of all, are we told that the vaccine works for 6 out of 10 people or that it did not work for 4 people?
Will you be told that the number of influenza cases has been cut in half, from 2.3 to 1%, or will you be told that the change is so slight?
This depends on how you perceive the information.
