Risk Factors for Severe Disease
COVID-19 poses an enormous threat to public health worldwide, and the experience of poor prognosis and high fatality rates from some severe cases makes it important to elucidate the risk factors for severe COVID-19 in order to predict and prevent disease progression and reduce fatality rates. This study will focus on analyzing the characteristics of COVID-19 cases and investigating the risk factors for developing severe COVID-19.
Study Description
This is disease surveillance data on symptomatic cases of COVID-19 reported from 30 provinces in China between January 19, 2020 and March 9, 2020, including demographics, date of symptom onset, clinical symptoms at diagnosis, and laboratory findings. and moderate cases were grouped as non-severe cases, and severe cases were classified as severe.
As a result.
A total of 12,647 people were included in the survey, and the number of severe cases was 1662 (13.1%). The median age range for severe cases was 57 years, while the median age for non-severe cases reported was 43 years.
The risk factors for severe disease were.
・Males [adjusted odds ratio (a OR) = 1.3, 95% CI: 1.2-1.5].
・Fever (OR = 2.3, 95% CI: 2.0 to 2.7)
・Cough (OR = 1.4, 95% CI: 1.2-1.6)
・Fatigue (OR = 1.3, 95% CI: 1.2-1.5)
・Chronic kidney disease (OR = 2.5, 95% CI: 1.4-4.6)
・Hypertension (OR = 1.5, 95% CI: 1.2-1.8)
・Diabetes mellitus (OR = 1.96, 95% CI: 1.6-2.4)
The results showed that
In addition, it is reported that the risk increases progressively with increasing age.
20-39 years old (OR = 3.9, 95% CI: 1.8-8.4)
40-59 years (OR = 7.6, 95% CI: 3.6-16.3)
60 years and older (OR = 20.4, 95% CI: 9.5-43.7)
And delayed diagnosis was also a factor in the onset of the disease.
3 to 5 days (OR = 1.4, 95% CI: 1.2-1.7)
6 - 8 days (a OR = 1.8, 95% CI: 1.5 - 2.1)
9 days (a OR = 1.9, 95% CI: 1.6-2.3)]
Conclusion.
From this study, the above mentioned factors have been mentioned as risk factors and based on these factors, we can predict the severity of the disease.
Geng, MJ., Wang, LP., Ren, X., et al. Risk factors for developing severe COVID-19 in China: an analysis of disease surveillance data. Infect Dis Poverty 10, 48 (2021). https://doi.org/10.1186/s40249-021-00820-9
Summary.
This study was published on April 12, 2021, so is this a similar risk factor for the mutant strains that are currently spreading? This study was published on April 12, 2021.
However, there are some research results that support the risk factors that have been reported for a long time, so people who are affected by these factors should not take it lightly.
